The Changes of Reflux Symptoms and Laryngoscopic Findings in Treatment of Patients with Laryngopharyngeal Reflux

Tae, Kyung; Lee, Yong-Seop; Jeong, Jin-Hyeok; Park, In-Beom; Lee, Seung-Hwan; Kim, Kyung-Rae

J Korean Soc Laryngol Phoniatr Logop > Volume 16(1); 2005 > Article

Journal of The Korean Society of Laryngology, Phoniatrics and Logopedics 2005;16(1): 15-18.

인후두 역류증의 치료 시 증상과 후두내시경 소견의 변화

태경, 이용섭, 정진혁, 박인범, 이승환, 김경래

한양대학교 의과대학 이비인후-두경부외과학교실

The Changes of Reflux Symptoms and Laryngoscopic Findings in Treatment of Patients with Laryngopharyngeal Reflux

Kyung Tae, Yong-Seop Lee, Jin-Hyeok Jeong, In-Beom Park, Seung-Hwan Lee, Kyung-Rae Kim

Department of Otolaryngology-Head and Nech Surgery, College of Medicine, Hanyang University

ABSTRACT

Background and Objectives
: To determine the changes of reflux symptoms and laryngoscopic findings of patients with laryngopharyngeal reflux (LPR) on the duration of proton pump inhibitor medication.
Materials and Method
s : From Feb 2003 to Nov 2004, 58 patients who were diagnosed with LPR by 24-hour double-probe pH monitoring were enrolled. All patients were treated with proton pump inhibitor and followed up for 8 weeks at least. The response of symptoms and laryngoscopic findings of patients were assessed with reflux symptom index (RSI) and reflux finding score (RFS) before treatment and 2, 4, 8, 12, 16, 20 weeks after treatment.
Results
: The symptoms of patients with LPR were improved significantly at 2, 4, 8 weeks of treatment. The laryngoscopic findings of patients with LPR were improved significantly at 4 and 12 weeks of treatment. There was no correlation between improvement of reflux symptoms and laryngoscopic findings.
Conclusion
s : The laryngoscopic findings of LPR patients were improved more slowly than reflux symptoms. Based on our results, anti-reflux therapy might be continued at least for 3 months until the improvement of laryngoscopic findings.

KEY WORDS： laryngopharngeal reflux;Proton pump inhibitor;Reflux symptom;Reflux finding score;