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J Korean Soc Laryngol Phoniatr Logop > Volume 27(1); 2016 > Article
Journal of The Korean Society of Laryngology, Phoniatrics and Logopedics 2016;27(1): 5-10.
전신질환과 관련된 음성장애의 치료
가천대학교 의과대학 길병원 이비인후-두경부외과학교실
The Management of Systemic Voice Disorders
Joo Hyun Woo
Department of Otolaryngology-Head & Neck Surgery, Gachon University, School of Medicine, Gil Medical Center, Incheon, Korea
 Revised: May 18, 2016   Accepted: 23 May 2016.  Published online: 30 June 2016.
Variable systemic diseases affect larynx and vocal fold and result in voice change. Asthma and chronic obstructive pulmonary disease make increase of intra-abdomimal pressure followed by reflux of gastric acid, which stimulate vagal-bronchopulomary reflex aggravating cough and respiratory disturbance. Fungal laryngitis in the general population is extremely rare, but can occur in immunocompromised AIDS patients. Although, initially, empirical antifungal therapy for candidiasis is often given without biopsy, diagnostic direct laryngoscopy and biopsy is imperative if a substantial clinical response is not rapidly achieved. In the highly active anti-retroviral therapy era, HIV-positive patients are living longer and are at higher risk for developing non-AIDS-defining malignancies. The incidence of head and neck cancer (HNC) which is related with human papilloma virus infection has increased. The survival is significantly lower among the AIDS-HNC patients with CD4 counts ≤200 cells/μL. Rheumatoid arthritis (RA) cause voice disturbance by developing cricoarytenoid joints fixation or nodule on vocal fold. Post-menopausal voice disorder (PMVD) is caused by decreased secretion of estrogen-progesterone resulting in decrease of fundamental frequency (F0). Hormonal replacement therapy is helpful to reduce F0 decrease. RA and PMVD result in slight voice change, but it could crucial in professional voice user.
KEY WORDS: SystemicDiseaseVoice disorder
중심 단어: 전신질환음성장애
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