Distribution of Autonomic Neurotransmitters in the Human Vocal Fold

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J Korean Soc Laryngol Phoniatr Logop > Volume 10(1); 1999 > Article

Journal of The Korean Society of Laryngology, Phoniatrics and Logopedics 1999;10(1): 37-42.

인간의 성대조직에서 자율신경 전달물질의 분포

조정일, 박정선, 김영모

인하대학교 의과대학 이비인후과학교실

Distribution of Autonomic Neurotransmitters in the Human Vocal Fold

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ABSTRACT

The vocal fold has three major function-phonation, respiration and protection, and is richly innervated. The vocal 1314 its autonomic innervation-adrenergic and cholinergic from superior cervical ganglion and the vagus nerve, respectively. The action of both system account for vasoregulation and glandular activity. In e vocal fold several kin of neuropeptides, including SP, CGRP, VIP, TH, NPY, ENK have been reported at the animal including cat or dog. But information regarding the distribution of autonomic nerve fibers containing neuropeptides in the human vocal fold is lacking. Two neuropeptides are of special interest : 1) vasoactive intestinal polypeptide(VIP)that is known to be contained in the parasympathetic(cholinergic) neuron. 2) tyrosine hydroxylase(TH)is located in the cytoplasm of noradrenergic neuron and is the rate-limiting enzyme in noradrenaline synthesis. To understand specific autonomic function of vocal fold we did immunohistochemical examination of VIP and TH in the human vocal fold.

KEY WORDS： Human vocal fold;Autonomic neurotransmitter;