Treatment of Vocal Fold Granuloma Using Botulinum Toxin Type A Injection

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J Korean Soc Laryngol Phoniatr Logop > Volume 11(2); 2000 > Article

Journal of The Korean Society of Laryngology, Phoniatrics and Logopedics 2000;11(2): 185-187.

A형 보툴리눔독소로 주입치료한 성대 육아종 1예

오종석, 전희선, 윤현철, 유종범, 최홍식

연세대학교 의과대학 이비인후과학교실, 음성언어의학연구소

Treatment of Vocal Fold Granuloma Using Botulinum Toxin Type A Injection

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ABSTRACT

The etiology of vocal fold granuloma was identified : post-endotracheal intubation, vocal abuse, acid reflux and idiopathic. The identification of the cause or causal factor is important, since the treatment must be fundamental directed at them. Treatment have included voice therapy and antireflux measures. Surgical excision is considered in patients who do not respond to medical management. In this study, a case of vocal fold granuloma resolved who underwent injection of the affected vocal fold. Botulinum toxin type A is probably successful by decreasing the strength during adduction in the arytenoid region which, when very intense, would perpetuate the granuloma. Localized injection of this neurotoxin is promising both as an initial treatment and as an alternative treatment in patients who do not respond to standard therapy.

KEY WORDS： Vocal fold granuloma;Type A botulinum toxin injection;

중심 단어： 성대 육아종;A형 보툴리눔독소 주사;