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J Korean Soc Laryngol Phoniatr Logop > Volume 22(1); 2011 > Article
Journal of The Korean Society of Laryngology, Phoniatrics and Logopedics 2011;22(1): 34-39.
토끼 후두내 삽입한 풍선도관에 대한 단기 조직 반응
유영삼1, 최찬1, 김동원2
1인제대학교 의과대학 상계백병원 이비인후과학교실
2인제대학교 의과대학 상계백병원 흉부외과학교실
Soft Tissue Response of Rabbit Larynx to Implanted Foley Catheter for Short Duration
Young-Sam Yoo1, Chan Choi1, Dong-Won Kim2
1Department of Otolaryngology Head and Neck Surgery, Sanggye Paik Hospital, College of Medicine, Inje University
2Department of Thoracic and Cardiovascular Surgery, Sanggye Paik Hospital, College of Medicine, Inje University
ABSTRACT
Objectives : This study was aimed to investigate soft tissue reaction such as inflammation, immune reaction of rabbit larynx to implanted foley catheter. Methods : After 8 rabbits were anesthetized, their thyroid cartilage and trachea were exposed through a skin incision and a 6 French foley catheter was inserted into the thyroid cartilage via cricothyroid membrane and ballooned with normal saline (0.1 mL). The other end of catheters were ligated and cut. The wound was closed keeping catheter under the skin. Two rabbits were used as normal control Larynges were removed for pathologic examination at 4weeks and 8 weeks of the study respectively,
Results
: Ten rabbits were euthanized for gross and pathologic examination (5 rabbits after 4 weeks and 5 rabbits after 8 weeks). All rabbits survived the study periods and inflammations or foreign body reactions were minimally found on pathologic examinations.
Conclusion
s : Foley catheter could be useful and safe material for vocal fold medialization in rabbit models.
KEY WORDS: Rabbit;Larynx;Medialization laryngoplasty;Foley catherer;
중심 단어: 토끼;후두;후두성형술;도뇨관;
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