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J Korean Soc Laryngol Phoniatr Logop > Volume 24(1); 2013 > Article
Journal of The Korean Society of Laryngology, Phoniatrics and Logopedics 2013;24(1): 33-40.
적갑상선 전절제술 환자의 방사성 동위원소치료 전.후 음성의 변화에 대한 연구
홍기환1, 서은지1, 이현두2, 윤연섭2, 임석태1
1전북대학교 임상의학연구소-전북대학교병원 의생명연구원
2전북대학교 이비인후과학교실
Voice Analysis before and after Radioactive Iodine Ablation in Patients with Total Thyroidectomy
Ki Hwan Hong1, Eun Ji Seo1, Hyun Doo Lee2, Yun Sub Yoon2, Seok Tae Lim1
1Research Institute of Clinical Medicine of Chonbuk National University-Biomedical Research Institute of Chonbuk National University Hospital
2Otolaryngology-HNS, Chonbuk National University Medical School
Background and Objectives:
This study is to objectively compare and analyze the acoustic changes in the patients with total thyroidectomy before and after RI therapy. Subjects and
For this study, a total of 50 patients with total thyroidectomy were participated as subjects. Voice samples were obtained at the time of post-operation (Post-OP), before high-dose radioactive iodine therapy (Pre-RIT), and after high-dose radioactive iodine therapy (Post-RIT). Acoustic analysis, the maximum phonation time and K-VHI (Korea-Voice handicap index) were used for subjective evaluation.
According to the comparison analysis of the three periods, mFo (Hz) was significantly reduced in all of the vowels /a/ and /i/ as the hormone was discontinued. This can be related to the reduction in vocal range. As thyroid hormone was discontinued, Shim (%) and APQ (%) values, which are the parameters related to the degree of aggressiveness, showed a significant increase in the middle vowel /a/. As thyroid hormone was discontinued, emotional index was significantly decreased in VHI (voice handicap index).
These results can be assumed that thyroid hormone suspension is related to the increased changes in the vocal intensity, the increase in noise and the reduction in vocal range. Emotionally, these data can be assumed that the responsive factors of one's own voice disorders were significantly decreased in the patients with vocal handicap.
KEY WORDS: Total thyroidectomy;Radioactive iodine therapy;Voice;
중심 단어: 갑상선 전절제술;방사선 요오드치료;음성분석;
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