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J Korean Soc Laryngol Phoniatr Logop > Volume 28(2); 2017 > Article
Journal of The Korean Society of Laryngology, Phoniatrics and Logopedics 2017;28(2): 144-147.
doi: https://doi.org/10.22469/jkslp.2017.28.2.144
흡인성 화상을 입은 환자에서 관찰된 후두점막의 악성변화 1례
이재영, 이길준, 안동빈, 손진호
경북대학교 의학전문대학원 칠곡경북대학교병원 이비인후과-두경부외과학교실
A Case of Malignant Transformation of Layngeal Mucosa after Inhalation Injury 25 Years Ago
Jae Young Lee, GilJoon Lee, Dongbin Ahn, Jin Ho Sohn
Department of Otorhinolaryngology-Head and Neck Surgery, Kyungpook National University School of Medicine, Kyungpook National University Chilgok Hospital, Daegu, Korea
Correspondence  Jin Ho Sohn ,Tel: (053) 200-216, Fax: (053) 200-2027, Email: sohnjh@knu.ac.kr
Received: 25 October 2017; Revised: November 7, 2017   Accepted: 25 November 2017.  Published online: 31 December 2017.
ABSTRACT
Laryngeal neoplasm is the second most common malignancy of the upper aerodigestive tract. About 85% to 95% of laryngeal malignancies are squamous cell carcinoma that arises from the epithelial lining of the larynx. The exact cause of laryngeal neoplasm is unknown, but certain risk factors can affect the chances of developing it. Chronic inflammation is a mutagen factor confirmed in the carcinogenesis of various tumor. Inhalation injuries cause histopathologic damage to laryngeal mucosa and inflammation change. This long term inflammation may leads to the development of dysplasia and malignant transformation. Recently, we experienced a case of malignant transformation of laryngeal mucosa after inhalation injury patient 25 years ago. Herein, we reported this rare case and review the relevant literature.
KEY WORDS: BurnLaryngeal neoplasmsInhalation injuryMalignant transformation
중심 단어: 화상후두 종양흡인성 손상악성변화
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