Relationship between Ambulatory 24-hour Double Probe pH Monitoring and Reflux Finding Score in Patients with LPR

Park, Young-Dae; Kang, Dae-Woon; Lee, Jin-Choon; Lee, Byung-Joo; Wang, Soo-Geun; Kim, Gwang-Ha

J Korean Soc Laryngol Phoniatr Logop > Volume 19(2); 2008 > Article

Journal of The Korean Society of Laryngology, Phoniatrics and Logopedics 2008;19(2): 136-141.

인후두 역류환자에서 이동성 24시간 이중 탐침 산도 검사와 인후두 역류 소견 점수와의 상관관계

박영대¹, 강대운¹, 이진춘¹, 이병주¹, 왕수건¹, 김광하²

¹부산대학교 의학전문대학원 이비인후과학교실
²부산대학교 의학전문대학원 내과학교실

Relationship between Ambulatory 24-hour Double Probe pH Monitoring and Reflux Finding Score in Patients with LPR

Young-Dae Park¹, Dae-Woon Kang¹, Jin-Choon Lee¹, Byung-Joo Lee¹, Soo-Geun Wang¹, Gwang-Ha Kim²

¹Department of Otorhinolaryngology-Head and Neck Surgery, Pusan National University School of Medicine
²Department of Internal Medicine, Pusan National University School of Medicine

ABSTRACT

Background and Objectives:
Laryngopharyngeal reflux (LPR) is a very common disease among outpatients of department of otorhinolaryngology. Although there are several diagnostic tools for LPR disease and ambulatory 24-hour double-probe pH monitoring is gold standard method, empirical diagnosis by reflux symptom index and reflux finding score (RFS) are mainly used. So we analyzed the relationship between ambulatory 24-hour double-probe pH monitoring and RFS in patients with LPR. Subjective and Method: Fifty patients with LPR symptoms and abnormal RFS and ambulatory 24-hour double probe monitoring were enrolled. Each items and sum of laryngeal reflux score were compared the results of ambulatory 24-hour double-probe pH monitoring in upper (UES) and lower (LES) esophageal sphincter.
Results:
There were no significant correlation between the results of ambulatory 24-hour double-probe pH monitoring in UES (pH<4 and pH<5) and each item and sum of RFS. However, supine time and reflux number of UES (pH<5) were showed the partial correlations with diffuse laryngeal edema and thick endolaryngeal mucus (p=0.03, p=0.01). Although there were no relationship between the results of ambulatory 24-hour double-probe pH monitoring in LES and sum of RFS, the significant correlations presented between granuloma and total time (p=0.008), upright time (p=0.008, reflux number (p=0.049) of LES.
Conclusion:
Although granuloma among items of RFS showed significantly correlation with the results of ambulatory 24-hour double-probe pH monitoring in LES, there were no significant correlation between the results of ambulatory 24-hour double-probe pH monitoring in UES and LES and items and sum of RFS.

KEY WORDS： Laryngopharyngeal reflux disease;Reflux finding score;Ambulatory 24-hour double-probe pH-monitoring;

중심 단어： 인후두역류;역류소견점수;이동성 24시간;이중탐침산도 검사;